Review



codon optimized mouse 5-ht 3a r gene (ncbi reference sequence: nm_001099644.1)  (GenScript corporation)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    GenScript corporation codon optimized mouse 5-ht 3a r gene (ncbi reference sequence: nm_001099644.1)
    Sequence of mouse 5-HT <t> 3A R </t> used in the cryo-EM study and the data on cryo-EM and refinement. a, Full length mouse 5-HT <t> 3A R </t> sequence used in the cryo-EM study. Regions in the sequence highlighted in green, blue, gray, and yellow represent strep-tag, linker, TEV cleavage site, and 1D4-tag, respectively. Secondary structural elements as seen in State 1 are plotted above the sequence. Loops in gray color are not seen in the final refined structure. All the important loops, sheets, and helices are labeled. Glycosylation sites are marked as blue arrows. Key residues within the serotonin-binding sites are highlighted in brown color. Cysteines present in the cys-loop are shown as cyan color. Pore-facing residues in M2 are shown in green color. Arg416 in the ICD is shown in red. b, Cryo-EM data collection, refinement and validation statistics.
    Codon Optimized Mouse 5 Ht 3a R Gene (Ncbi Reference Sequence: Nm 001099644.1), supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/codon-optimized+mouse+5-ht+3a+r+gene+%28ncbi+reference+sequence%3A+nm_001099644%2E1%29/pmc06237196-55-0-15?v=GenScript+corporation
    Average 90 stars, based on 1 article reviews
    codon optimized mouse 5-ht 3a r gene (ncbi reference sequence: nm_001099644.1) - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT 3A receptor"

    Article Title: Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT 3A receptor

    Journal: Nature

    doi: 10.1038/s41586-018-0660-7

    Sequence of mouse 5-HT 3A R used in the cryo-EM study and the data on cryo-EM and refinement. a, Full length mouse 5-HT 3A R sequence used in the cryo-EM study. Regions in the sequence highlighted in green, blue, gray, and yellow represent strep-tag, linker, TEV cleavage site, and 1D4-tag, respectively. Secondary structural elements as seen in State 1 are plotted above the sequence. Loops in gray color are not seen in the final refined structure. All the important loops, sheets, and helices are labeled. Glycosylation sites are marked as blue arrows. Key residues within the serotonin-binding sites are highlighted in brown color. Cysteines present in the cys-loop are shown as cyan color. Pore-facing residues in M2 are shown in green color. Arg416 in the ICD is shown in red. b, Cryo-EM data collection, refinement and validation statistics.
    Figure Legend Snippet: Sequence of mouse 5-HT 3A R used in the cryo-EM study and the data on cryo-EM and refinement. a, Full length mouse 5-HT 3A R sequence used in the cryo-EM study. Regions in the sequence highlighted in green, blue, gray, and yellow represent strep-tag, linker, TEV cleavage site, and 1D4-tag, respectively. Secondary structural elements as seen in State 1 are plotted above the sequence. Loops in gray color are not seen in the final refined structure. All the important loops, sheets, and helices are labeled. Glycosylation sites are marked as blue arrows. Key residues within the serotonin-binding sites are highlighted in brown color. Cysteines present in the cys-loop are shown as cyan color. Pore-facing residues in M2 are shown in green color. Arg416 in the ICD is shown in red. b, Cryo-EM data collection, refinement and validation statistics.

    Techniques Used: Sequencing, Strep-tag, Labeling, Glycoproteomics, Biomarker Discovery



    Similar Products

    Image Search Results